The Cornell High Energy Synchrotron Source is a high-intensity high-energy X-ray source supported by the National Science Foundation. CHESS provides our users state-of-the-art synchrotron radiation facilities for research in Physics, Chemistry, Biology, and Environmental and Materials Sciences. A special NIH Research Resource, called MacCHESS, supports special facilities for protein crystallographic studies. CHESS serves a wide spectrum of experimental groups from Universities, National Laboratories and Industry, with 500-600 scientists and training scientists each year visiting CHESS's 12 endstations to collect data. In addition, a significant effort of the staff is aimed at developing synchrotron radiation experimental facilities and methods that utilize the high intensity photon flux provided by the Cornell Electron Storage Ring (CESR).